The implementation plan is divided into 6 work packages (WPs). No Work Package Title Lead Beneficiary WP1 Managemen, communication & Dissemination FORTH WP2 Identification of key cytochrome P450s involved in xenobiotic metabolism - toxicity and selectivity EXETER WP3 Development of cell and recombinant enzyme-based tools for high throughput screens CYPEX WP4 Development by design of selective and safe insecticides and synergies SYNGETA-CH WP5 Validation of selective (pro)insecticides and synergists MAGMA WP6 Training, knowledge integration & Exploitation GHENT